Mean daily dose is 12-15 g of milk thistle fruit or 200-400 mg of sylimarin, as calculated per silibinin.1 Sylimarin is poorly water-soluble, so extracts and tinctures contain much more of the agent compared to infusions. 2 The best effects are achieved when milk thistle is used for longer periods of time – 2-3 months.
Milk thistle fruit should be pulverised in a mortar, crushed or milled. Pour 1 glass of hot water onto 1 teaspoonful of the powder (3–5 g) and heat until it boils. Simmer over low heat, covered, for 5-10 minutes. Leave for 15 min and filter.
In cases of poisoning, liver and gallbladder conditions, indigestion: drink a glass of the decoction three times a day, half an hour before a meal (that is 3 teaspoonfuls of milk thistle fruit daily).
As an antihaemorrhagic agent: drink 1 tablespoonful every 1 hour.
In case of preventive use the dose may be reduced: drink half a glass of decoction two times a day (that is 1 teaspoonful of milk thistle fruit a day).
Powdered milk thistle seeds may be also consumed directly, 12-15 g a day (approximately 1 tablespoonful).
Milk thistle fruit should be crushed in a mortar or milled into powder. Transfer the powder into a glass vessel and add 40% alcohol, keeping a proportion of 1:10. Leave for 3 weeks, shake regularly. Then filter and pour into bottles fitted with a dropper. For digestion disorders, migraine or varicose veins, take 15-25 drops of the tincture 3 times a day. The tincture contains alcohol, therefore it cannot be used in case of liver cirrhosis!